Thermo Fisher Scientific ANAPC11 Monoclonal Antibody (OTI3F5), TrueMAB
인간 ANAPC11 단백질을 인식하는 Mouse monoclonal 항체. Western blot, IHC(P), ICC/IF에 사용 가능. TrueMAB 포맷으로 높은 특이성과 재현성 제공. 세포 주기 관련 단백질 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F5 |
| Immunogen | Full length human recombinant protein of human ANAPC11 produced in HEK293T cell. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Together with the cullin protein ANAPC2, ANAPC11 constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex mediates ubiquitination and subsequent degradation of target proteins, mainly forming Lys-11-linked polyubiquitin chains and, to a lower extent, Lys-48- and Lys-63-linked chains. It may also recruit E2 ubiquitin-conjugating enzymes to the complex.
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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