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Thermo Fisher Scientific XPF Polyclonal Antibody
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Thermo Fisher Scientific의 XPF 폴리클로날 항체는 인간 XPF 단백질의 C-말단 영역을 인식합니다. Western blot에 적합하며, 다양한 종에서 예측 반응성을 보입니다. 고순도 항원 친화 크로마토그래피 정제, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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마지막 업데이트 2025. 08. 04. 오전 11:59
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Thermo Fisher Scientific PA577973 XPF Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
731,200원VAT 포함 804,320원
Thermo Fisher Scientific · Thermo Fisher Scientific XPF Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the C-terminus region of human XPF. The exact sequence is proprietary. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2736808 |
Product Specific Information
- Positive Control: 293T, A431, HeLa, HepG2
- Predicted Reactivity: Mouse (84%), Chicken (83%), Bovine (88%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA:
- Nucleotide Excision Repair (NER) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand cross-links
In mammalian cells:
- XPG cleaves 3' of the DNA lesion
- ERCC1/XPF complex makes the 5' incision
ERCC1/XPF likely contributes to processing partially repaired recombination intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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