Thermo Fisher Scientific COPE Polyclonal Antibody
Thermo Fisher Scientific의 COPE Polyclonal Antibody는 인간 COPE 단백질에 특이적인 토끼 IgG 항체입니다. Western blot, IHC, ICC/IF 등 다양한 응용에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용되며 장기 보관 시 -20°C에서 안정적으로 저장 가능합니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human COPE. Recombinant protein control fragment (Product #RP-102946). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640059 |
Product Specific Information
Immunogen sequence:
GSGEVDELFD VKNAFYIGSY QQCINEAQRV KLSSPERDVE RDVFLYRAYL AQRKFGVVLD EIKPSSAPEL QAVRMFADYL
Sequence identity:
- Mouse: 96%
- Rat: 95%
Target Information
The COPE gene encodes the epsilon subunit of the coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and associates with Golgi non-clathrin-coated vesicles. It is essential for budding from Golgi membranes and retrograde Golgi-to-ER transport of dilysine-tagged proteins. The coatomer complex includes alpha, beta, beta’, gamma, delta, epsilon, and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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