Thermo Fisher Scientific LGR7 Polyclonal Antibody
Thermo Fisher Scientific의 LGR7 폴리클로날 항체는 인간 및 돼지 시료에 반응하며, IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 액상 형태의 비결합 항체로, 1 mg/mL 농도를 유지합니다. 단기 4°C, 장기 -20°C 보관이 권장됩니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 40 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Pig |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from N-terminal extracellular domain of human RXFP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551523 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Marmoset, Panda, Pig (100%)
Orangutan, Monkey, Rat, Bovine, Dog, Horse (95%)
Target Information
LGR7 is a low density lipoprotein receptor of 757 amino acids belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity.
It has seven transmembrane regions, a cysteine-rich motif, 10 LRR domains, and 5 N-glycosylation sites in the N terminus.
Research reports show that it acts as a receptor for relaxins (RLN1 and RLN2), stimulating adenylate cyclase activation, substrate adhesion, and chemo migratory capacity of mononuclear leukocytes.
LGR7 is critical for mediating these biological responses via RNA interference lentiviral short hairpin constructs.
It is widely expressed in 86% of 15 primary EC tissue samples including brain, kidney, testis, and endometrium.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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