Thermo Fisher Scientific LGR7 Polyclonal Antibody
Thermo Fisher Scientific의 LGR7 Polyclonal Antibody는 인간 RXFP1의 C-말단 펩타이드를 면역원으로 한 토끼 IgG 항체입니다. IHC(P)에서 20 µg/mL로 검증되었으며, 액상 형태로 제공됩니다. 항원 친화 크로마토그래피로 정제되었고, 연구용으로 적합합니다.
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Thermo Fisher Scientific LGR7 Polyclonal Antibody
Applications and Tested Dilution
- Immunohistochemistry (Paraffin) (IHC (P)): 20 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 19 amino acid peptide from C-terminus of human RXFP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551522 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Orangutan: 100%
- Gibbon, Monkey: 95%
- Marmoset: 84%
Target Information
LGR7 is a low density lipoprotein receptor of 757 amino acids belonging to the G-protein coupled receptor 1 family with rhodopsin-like receptor activity.
It has seven transmembrane regions, a cysteine-rich motif, 10 LRR domains, and 5 N-glycosylation sites in the N terminus.
Research reports show that it acts as a receptor for relaxins (RLN1 and RLN2), stimulating adenylate cyclase activation, substrate adhesion, and chemomigratory capacity of mononuclear leukocytes.
LGR7 is critical for mediating these biological responses using RNA interference lentiviral short hairpin constructs.
It is widely expressed in 86% of 15 primary EC tissue samples, including brain, kidney, testis, and endometrium.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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