Thermo Fisher Scientific Influenza A NP Recombinant Rabbit Monoclonal Antibody (HL1078)

Applications and Tested Dilution

Product Specifications

Product Specific Information

Store as concentrated solution. Centrifuge briefly prior to opening vial.
For short-term storage (1–2 weeks), store at 4°C.
For long-term storage, aliquot and store at -20°C or below.
Avoid multiple freeze-thaw cycles.

Target Information

The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle.
As well as binding ssRNA, NP is able to self-associate to form large oligomeric complexes. NP interacts with various viral and cellular macromolecules, including PB1 and PB2 subunits of the polymerase and the matrix protein M1.
NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1, and a DEAD box helicase BAT1/UAP56 (Portela et al., 2002).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.