Thermo Fisher Scientific RPL36 Polyclonal Antibody
RPL36 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P) 검증 완료. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol 용액 형태로 제공되며, 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human RPL36. Recombinant protein control fragment (Product #RP-100805) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2646745 |
Product Specific Information
- Immunogen sequence: MELLKVSKDK RALKFIKKRV GT
- Antigen sequence identity: Mouse – 100%, Rat – 100%
Target Information
The exosome is involved in numerous cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of various RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed, with the highest expression in testis, and is essential for processing 7S pre-RNA into a mature nuclear complex, contributing to proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role in tumorigenesis.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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