Thermo Fisher Scientific Carbonic Anhydrase VB Polyclonal Antibody
Thermo Fisher Scientific의 Carbonic Anhydrase VB Polyclonal Antibody는 인간 및 마우스에 반응하는 토끼 IgG 항체로, WB, IHC, Flow Cytometry에 적합합니다. 미토콘드리아 내 CA VB 단백질을 표적하며, 대사 과정 연구에 유용합니다. 액상 형태로 2 mg/mL 농도이며, 장기 보관 시 -20°C에서 보관합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | 1:10–1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide between 253–283 amino acids from the C-terminal region of human CA5B |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2543444 |
Product Specific Information
This antibody is predicted to react with rat based on sequence homology.
Target Information
Carbonic anhydrases (CAs) are zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They exhibit diversity in distribution and subcellular localization and are involved in processes such as calcification, bone resorption, respiration, acid-base balance, and formation of aqueous humor, saliva, gastric juice, and cerebrospinal fluid.
CA VB (Carbonate Dehydratase VB) is a mitochondrial isoform of CA V, predominantly expressed in heart, pancreas, lung, placenta, kidney, and skeletal muscle. It shows high homology with CA VA but is not expressed in the liver, indicating a distinct physiological role.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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