Thermo Fisher Scientific IFIT1 Polyclonal Antibody
Human IFIT1 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 안정화 버퍼 포함. 바이러스 RNA 감지 연구 및 인터페론 관련 연구에 적합.
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Thermo Fisher Scientific IFIT1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 36–281 of Human IFIT1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2548728 |
Product Specific Information
- Recommended positive controls: HeLa, HeLa (10 ng/mL hIFN-gamma1 treatment for 16 hr)
- Predicted reactivity: Chimpanzee (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5′-triphosphate group (PPP-RNA). Acts as a sensor of viral single-stranded RNAs and inhibits expression of viral messenger RNAs. PPP-RNAs lack 2′-O-methylation and serve as a molecular signature distinguishing self from non-self mRNAs during viral infection. Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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