Thermo Fisher Scientific PRTFDC1 Polyclonal Antibody
PRTFDC1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. Human에 반응하며 Rat, Chicken에서도 예측 반응성을 보입니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 1–214 of Human PRTFDC1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2548725 |
Product Specific Information
- Recommended positive controls: NT2D1, IMR32, U87-MG
- Predicted reactivity: Rat (92%), Chicken (83%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Phosphoribosyl transferase domain containing 1 (PRTFDC1) is highly homologous to hypoxanthine phosphoribosyltransferase (HPRT1) and may have arisen from a gene duplication event. CpG islands in the PRTFDC1 promoter can be hypermethylated in ovarian cancers and oral squamous-cell carcinomas (OSCC), leading to gene silencing. Restoration of PRTFDC1 expression in OSCC inhibited cell growth, while knockdown promoted growth, suggesting a tumor-suppressor role. At least three isoforms of PRTFDC1 are known to exist.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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