Thermo Fisher Scientific Thymidine Phosphorylase Polyclonal Antibody
인간 Thymidine Phosphorylase를 인식하는 Rabbit Polyclonal 항체로, Western blot에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 보존제 없이 -20°C에서 보관합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
- Western Blot (WB): 1:1,000
- Referenced in publications (see references section)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues surrounding Gln370 of human TP/ECGF1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.01M HEPES, pH 7.5, 0.15M NaCl, 100 µg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_10984207 |
Product Specific Information
It is not recommended to aliquot this antibody.
Target Information
Thymidine phosphorylase (TP), also known as platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate.
It exhibits chemotactic and mitogenic activity for endothelial cells and functions as a non-heparin-binding angiogenic factor present in platelets.
Additionally, it plays a role in the activation of fluoropyrimidines, cytotoxic agents used in cancer therapy, converting them into active metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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