Thermo Fisher Scientific ACSL5 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 500-739 of human ACSL5 (NP_0573182) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ACSL5,uniProtId:Q9ULC5-1,ncbiNodeId:9606,antigenRange:444-683,antigenLength:683,antigenImageFileName:PA5-89639_ACSL5_Q9ULC5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89639_ACSL5_Q9ULC5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.74 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805705

Product Specific Information

Immunogen sequence: GQTECTGGCT FTLPGDWTSG HVGVPLACNY VKLEDVADMN YFTVNNEGEV CIKGTNVFKG YLKDPEKTQE ALDSDGWLHT GDIGRWLPNG TLKIIDRKKN IFKLAQGEYI APEKIENIYN RSQPVLQIFV HGESLRSSLV GVVVPDTDVL PSFAAKLGVK GSFEELCQNQ VVREAILEDL QKIGKESGLK TFEQVKAIFL HPEPFSIENG LLTPTLKAKR GELSKYFRTQ IDSLYEHIQD; Positive Samples: HL-60, Mouse liver, Rat liver; Cellular Location: Endoplasmic reticulum, Endoplasmic reticulum membrane, Mitochondrion, Mitochondrion outer membrane, Single-pass type III membrane protein

Target Information

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.