Thermo Fisher Scientific CK1 gamma-1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 298-422 of human CSNK1G1 (NP_0713312) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CK1 gamma-1,uniProtId:Q9HCP0-1,ncbiNodeId:9606,antigenRange:298-422,antigenLength:422,antigenImageFileName:PA5-89640_CK1_gamma-1_Q9HCP0-1_Rabbit.svg,antigenImageFileNamePDP:PA5-89640_CK1_gamma-1_Q9HCP0-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.74 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2805706

Product Specific Information

Immunogen sequence: FFEKPDYEYL RTLFTDLFEK KGYTFDYAYD WVGRPIPTPV GSVHVDSGAS AITRESHTHR DRPSQQQPLR NQVVSSTNGE LNVDDPTGAH SNAPITAHAE VEVVEEAKCC CFFKRKRKKT AQRHK; Positive Samples: Jurkat, MCF-7, Mouse spleen; Cellular Location: Cytoplasm

Target Information

Casein kinase I (also designated CKI) and casein kinase II (also designated CKII) compose a family of serine/ threonine protein kinases which are present in all eukaryotes examined to date. CKI family members, which include CKI alpha, gamma, epsilon and delta, have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. CKII is usually expressed as a tetrameric complex consisting of either an alpha2 beta2 or an alpha alpha` beta2 structure. The alpha catalytic subunit is stimulated by the beta regulatory subunit, which undergoes autophosphorylation. CKII activity is high in the cytosol and nucleus of proliferating and differentiating cells. CKII is known to phosphorylate more than 100 different substrates including nuclear oncoproteins, transcription factors and enzymes involved in DNA metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.