ELK Biotechnology UBE2D2 rabbit pAb
UBE2D2 rabbit pAb는 인간, 마우스, 랫트 시료에서 사용 가능한 다클론 항체로, 유비퀴틴-프로테아좀 시스템 연구에 적합합니다. Western blot과 ELISA에 활용되며, p53 및 PEX5 등의 단백질 분석에 유용합니다. -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology UBE2D2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | UBE2D2 rabbit pAb |
| Alternative Names | UBE2D2; UBC4; UBC5B; UBCH4; UBCH5B; Ubiquitin-conjugating enzyme E2 D2; Ubiquitin carrier protein D2; Ubiquitin-conjugating enzyme E2(17)KB 2; Ubiquitin-conjugating enzyme E2-17 kDa 2; Ubiquitin-protein ligase D2 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/10000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human UBE2D2 (AA range: 98–147) |
| Species Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 17 kD |
| GeneID (Human) | 7322 |
| Human Swiss-Prot No | P62837 |
| Cellular localization | Ubiquitin ligase complex, nucleoplasm, cytosol, protein complex, extracellular exosome |
| Species Reactivity | Human; Mouse; Rat |
Background
Regulated degradation of misfolded, damaged, or short-lived proteins in eukaryotes occurs via the ubiquitin (Ub)-proteasome system (UPS). An integral part of this system is the ubiquitination of target proteins and covalent linkage of Ub-containing proteins to form polymeric chains, marking them for 26S proteasome-mediated degradation. Ubiquitination is mediated by a cascade of enzymes including E1 (activating), E2 (conjugating), and E3 (ligases).
UBE2D2 encodes a member of the E2 enzyme family. Substrates include tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5). Alternative splicing results in multiple transcript variants of this gene.
[Provided by RefSeq, May 2013]
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