Thermo Fisher Scientific DHX29 Polyclonal Antibody
Rabbit polyclonal antibody targeting human DHX29 protein. Validated for Western blot and IHC applications. High specificity and purity via antigen affinity chromatography. Suitable for DNA helicase-related research and chromatin remodeling studies.
- 카탈로그번호
- PA558338
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human DHX29 (Control fragment: Product #RP-96813) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2640584 |
Product Specific Information
Immunogen sequence:
LQAFSFKTKD IEDAMTNTLL YGGDLHSALD WLCLNLSDDA LPEGFSQEFE EQQPKSRPKF QSPQIQATIS PPLQPKTK
Sequence identity:
- Mouse: 94%
- Rat: 95%
Target Information
DHX29 is a DNA helicase and probable scaffold component of the chromatin remodeling INO80 complex.
It plays roles in transcriptional regulation, DNA replication, and DNA repair.
According to PubMed:20687897, its contribution to DNA double-strand break repair is indirect, through transcriptional regulation.
Recruited by YY1 to YY1-activated genes where it acts as an essential coactivator.
Binds DNA and exhibits double-stranded DNA-dependent ATPase activity in vitro.
Involved in UV-damage excision repair, DNA replication, and chromosome segregation during the cell cycle.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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