Thermo Fisher Scientific HPD Polyclonal Antibody
Human HPD 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 및 글리세롤 완충액 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:20–1:50 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human HPD. Recombinant protein control fragment (Product # RP-97848) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2642532 |
Product Specific Information
Immunogen sequence:
MTTYSDKGAK PERGRFLHFH SVTFWVGNAK QATSFYCSKM GFEPLAYRGL ETGSREVVSH VIKQGKIVFV LSSALNPWNK EMGDHLVKHG DG
Antigen sequence identity:
- Mouse: 93%
- Rat: 93%
Target Information
The inhibitor of apoptosis (IAP) family of proteins regulates programmed cell death triggered by various stimuli. All IAPs have at least one baculovirus IAP repeat (BIR) motif that is essential for their anti-apoptotic activity.
A mitochondrial serine protease, Omi/HtrA2, is released upon apoptotic stimuli and binds to IAPs. Like Smac/DIABLO, Omi contains a conserved IAP-binding motif (AVPS) at its N-terminus. Deregulated expression of Omi in the cytoplasm induces apoptosis, suggesting its role in the mitochondrial apoptotic pathway.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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