ELK Biotechnology TGFβ1 rabbit pAb

제품명

TGFβ1 rabbit pAb

대체 명칭

TGFB1; TGFB; Transforming growth factor beta-1; TGF-beta-1

적용 분야 (Applications)

• Western Blot (WB)
• Immunohistochemistry (IHC)
• Immunofluorescence (IF)
• ELISA

권장 희석 배수 (Recommended Dilutions)

면역원 (Immunogen)

The antiserum was produced against synthesized peptide derived from human TGF beta1.
Amino acid range: 336-385

저장 조건 (Storage)

• 종: Rabbit
• 보관 온도: -20°C
• 보관 기간: 1년

항체 특성

유전자 정보

세포 내 위치 (Cellular Localization)

• Latency-associated peptide: Secreted, extracellular space, extracellular matrix
• Transforming growth factor beta-1: Secreted

배경 (Background)

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha.

종간 반응성 (Species Reactivity)

Human; Mouse; Rat