ELK Biotechnology RGS1 rabbit pAb
RGS1 rabbit pAb는 인간 RGS1 단백질을 인식하는 고품질 폴리클로날 항체입니다. WB, IHC, IF, ELISA에 적합하며 다양한 종(Human, Mouse, Rat)에 반응합니다. 세포막 및 세포질 단백질 검출에 유용하며 장기 보관(-20°C/1년)이 가능합니다.
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ELK Biotechnology RGS1 rabbit pAb
제품 개요
RGS1 rabbit pAb는 Regulator of G-protein signaling 1(RGS1)을 인식하는 폴리클로날 항체로, G단백질 신호 조절 연구에 적합합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | RGS1 rabbit pAb |
| Alternative Names | RGS1; 1R20; BL34; IER1; Regulator of G-protein signaling 1; B-cell activation protein BL34; Early response protein 1R20 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 Immunohistochemistry: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from human RGS1 (AA range: 118–167) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 22 kD |
| GeneID (Human) | 5996 |
| Human Swiss-Prot No | Q08116 |
| Cellular Localization | Cell membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasm, cytosol |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [Provided by RefSeq, Jul 2008]
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