ELK Biotechnology SOCS-1 rabbit pAb
SOCS-1 단백질을 인식하는 토끼 다클론 항체로, IF, WB, IHC, ELISA 등 다양한 응용 가능. 인간 SOCS-1 펩타이드로부터 제작되어 높은 특이성과 재현성을 제공. 세포 내 핵 및 세포질 소포체에 주로 위치하며, 사이토카인 신호 억제 연구에 적합.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology SOCS-1 rabbit pAb
제품명
SOCS-1 rabbit pAb
공급업체
ELK Biotechnology
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | SOCS1; SSI1; TIP3; Suppressor of cytokine signaling 1; SOCS-1; JAK-binding protein; JAB; STAT-induced STAT inhibitor 1; SSI-1; Tec-interacting protein 3; TIP-3 |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200; WB: 1:500–2000; ELISA: 1:10000–20000; IHC: 1:50–300 |
| Immunogen | Synthesized peptide derived from human SOCS-1 (AA range: 49–98) |
| Species Reactivity | Human; Mouse; Rat |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 38 kD |
| GeneID (Human) | 8651 |
| Human Swiss-Prot No | O15524 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Cellular Localization | Nucleus; Cytoplasmic vesicle; Detected in perinuclear cytoplasmic vesicles upon interaction with FGFR3 |
Background
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3, erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors and participates in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggest that this gene modulates IFN-gamma action, which is required for normal postnatal growth and survival. [RefSeq, Jul 2008]
제품 이미지
(이미지 정보가 제공되지 않았습니다)
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.