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ELK Biotechnology RUNX3 rabbit pAb
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RUNX3 단백질을 인식하는 토끼 다클론 항체로, Western blot과 ELISA에 적합합니다. 인간 RUNX3 유래 펩타이드로 면역화되었으며, 핵 및 세포질에서 발현되는 RUNX3 검출에 사용됩니다. 암 연구 및 전사 조절 연구에 유용합니다.
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ELK Biotechnology ES3400-100UL RUNX3 rabbit pAb, 100UL pk판매 단위 pk ·
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402,000원VAT 포함 442,200원
ELK Biotechnology ES3400-50UL RUNX3 rabbit pAb, 50UL pk판매 단위 pk ·
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301,000원VAT 포함 331,100원
ELK Biotechnology · ELK Biotechnology RUNX3 rabbit pAb
제품명
RUNX3 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | RUNX3; AML2; CBFA3; PEBP2A3; Runt-related transcription factor 3; Acute myeloid leukemia 2 protein; Core-binding factor subunit alpha-3; CBF-alpha-3; Oncogene AML-2; Polyomavirus enhancer-binding protein 2 alpha C subunit; PEA2-alpha C; PEB |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/40000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RUNX3 (AA range: 133–182) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kD |
| Gene ID (Human) | 864 |
| Human Swiss-Prot No. | Q13761 |
| Cellular Localization | Nucleus, Cytoplasm. The tyrosine phosphorylated form localizes to the cytoplasm. Translocates from the cytoplasm to the nucleus following TGF-beta stimulation. |
| Species Reactivity | Human; Mouse |
Background
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. (provided by RefSeq, Mar 2016)
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