Thermo Fisher Scientific GPI Monoclonal Antibody (OTI8G7), TrueMAB
GPI 단백질을 인식하는 Mouse monoclonal antibody로, WB, IHC, ICC, Flow Cytometry에 적합합니다. 고순도의 Lyophilized 형태로 제공되며, Human 시료에 반응합니다. 연구용으로 에너지 대사 관련 GPI 단백질 분석에 활용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI8G7 |
| Immunogen | Full length human recombinant protein of human GPI produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The GPI gene encodes a multifunctional phosphoglucose isomerase involved in energy metabolism.
This dimeric enzyme catalyzes the reversible isomerization of glucose-6-phosphate and fructose-6-phosphate.
- In the cytoplasm: functions in glycolysis and gluconeogenesis
- Extracellularly: acts as a neurotrophic factor for spinal and sensory neurons
Defects in this gene can cause nonspherocytic hemolytic anemia and, in severe cases, enzyme deficiency associated with hydrops fetalis, neonatal death, and neurological impairment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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