Thermo Fisher Scientific Glucagon Receptor Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

15-20 µg/mL

-

Product Specifications

Species Reactivity

Bovine, Dog, Horse, Hamster, Human, Non-human primate

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human Glucagon Receptor. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Glucagon Receptor,uniProtId:P47871-1,ncbiNodeId:9606,antigenRange:1,antigenLength:477,antigenImageFileName:PA5-33595_Glucagon_Receptor_P47871-1_Rabbit.svg,antigenImageFileNamePDP:PA5-33595_Glucagon_Receptor_P47871-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2550973

Product Specific Information

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Hamster, Bovine, Dog, Horse (100%) Mouse, Rat (94%).

Target Information

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.