Thermo Fisher Scientific Glucagon Receptor Polyclonal Antibody
Glucagon 수용체를 인식하는 Rabbit Polyclonal Antibody로 인간 및 비인간 영장류에 반응합니다. IHC(P)에서 13 µg/mL로 검증되었으며, 항원 친화 크로마토그래피로 정제되었습니다. PBS buffer에 0.1% sodium azide를 포함하며, 연구용으로 혈당 조절 관련 연구에 적합합니다.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): Tested dilution 13 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 18 amino acid peptide from N-terminal extracellular domain of human Glucagon Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550972 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Gorilla, Gibbon, Monkey (100%)
Horse, Opossum (94%)
Target Information
Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostasis.
They regulate hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis.
Glucagon receptors also mediate responses to fasting. Ligand binding induces conformational changes that trigger G-protein signaling and modulate downstream effector activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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