Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Chimeric Recombinant Rabbit Monoclonal Antibody (P06DHuRb)
SARS-CoV-2 스파이크 단백질 RBD를 인식하는 키메라형 재조합 토끼 단클론 항체. ICC, Flow, ELISA, 중화시험에 사용 가능. Expi293 발현, Protein A 정제, 비결합형 형태. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Flow Cytometry (Flow) | 0.01 µg/test |
| ELISA | 0.2–2,000 ng/mL |
| Neutralization (Neu) | 0.1–10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Virus |
| Host / Isotype | Rabbit / IgG, lambda |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | P06DHuRb |
| Immunogen | This antibody was developed using computationally derived variants of SARS-CoV antibody structures and is shown to bind Spike Protein S1 subunit (RBD) of SARS-CoV-2. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2866482 |
Product Specific Information
This antibody has a human Fab with a lambda light chain and a rabbit Fc region.
It specifically recognizes the receptor-binding domain (RBD) of the SARS-CoV-2 Spike protein.
It is recommended to titrate the antibody carefully for optimal assay performance.
This antibody is not recommended for Western blot applications.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, causes illnesses ranging from mild cold-like symptoms to severe respiratory distress and death.
The Spike (S) protein is crucial for viral attachment, fusion, and entry, making it a key target for antibody, inhibitor, and vaccine development.
The Receptor-Binding Domain (RBD) of the Spike protein binds strongly to human and bat ACE2 receptors, with higher affinity than that of SARS-CoV.
The S1 subunit contains the RBD responsible for specific ACE2 binding on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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