Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Recombinant Human Monoclonal Antibody (T01KHu)
SARS-CoV-2 Spike Protein RBD를 인식하는 인간 재조합 단클론 항체. 다양한 면역분석(ICC, Flow, ELISA 등)에 사용 가능. Expi293 시스템에서 발현된 IgG1, kappa 형식. 비결합(Unconjugated) 형태로 제공되며, 단백질 A로 정제됨. 연구용으로만 사용.
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Thermo Fisher Scientific SARS-CoV-2 Spike Protein (RBD) Recombinant Human Monoclonal Antibody (T01KHu)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunocytochemistry (ICC/IF) | 5 µg/mL | View 1 publication |
| Flow Cytometry (Flow) | 1 µg/test | View 2 publications |
| ELISA | 0.2–2,000 ng/mL | View 1 publication |
| Neutralization (Neu) | 0.1–10 µg/mL | - |
| Luminex (LUM) | 0.5 mg/mL | - |
| Not applicable (N/A) | - | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Virus |
| Published Species | Human, Virus |
| Host / Isotype | Human / IgG1, kappa |
| Expression System | Expi293 |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | T01KHu |
| Immunogen | Developed using computationally derived variants of SARS-CoV antibody structures; binds Spike Protein S1 subunit (RBD) of SARS-CoV-2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2866477 |
Product Specific Information
This antibody recognizes the RBD domain of the SARS-CoV-2 Spike protein.
It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.
This antibody is not recommended for Western blot application.
Target Information
SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), also known as 2019-nCoV, is a virus causing illnesses from mild cold symptoms to severe respiratory distress and death.
The Spike (S) protein is crucial for viral attachment, fusion, and entry, serving as a target for antibody and vaccine development.
The receptor-binding domain (RBD, S-RBD) in the Spike protein binds strongly to human and bat ACE2 receptors, showing higher affinity than SARS-CoV RBD.
The S1 subunit contains the RBD that specifically interacts with ACE2 receptors on target cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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