Thermo Fisher Scientific CD9 Monoclonal Antibody (MEM-61), Biotin
CD9 단백질의 EC2 도메인을 인식하는 Biotin 결합 단클론 항체로, 인간 시료에 반응합니다. Western blot, IHC, Flow Cytometry, ELISA 등 다양한 응용에 적합합니다. 액상 형태, 1 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Flow Cytometry (Flow) | 2–5 µg/mL |
| ELISA | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MEM-61 |
| Immunogen | Pre-B cell line NALM-6 |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Size-exclusion chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 15 mM sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073471 |
Additional Formats:
Product Specific Information
This antibody recognizes an epitope on the second extracellular domain (EC2) of CD9 antigen, a 24 kDa transmembrane protein expressed on platelets, monocytes, pre-B lymphocytes, granulocytes, and activated T lymphocytes.
Target Information
CD9 antigen is a glycoprotein expressed on the surface of developing B lymphocytes, platelets, monocytes, eosinophils, basophils, stimulated T lymphocytes, and by neurons and glial cells in the peripheral nervous system.
CD9 belongs to the tetraspanin family of membrane proteins that traverse the membrane four times.
In pre-B cells and platelets, CD9 regulates cell activation and aggregation through association with integrins CD41/CD61 (GPIIb/GPIIIa).
It is involved in cell motility, osteoclastogenesis, neurite outgrowth, myotube formation, and sperm-egg fusion.
CD9 plays important roles in cell attachment, proliferation, and differentiation, and acts as a metastasis suppressor in solid tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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