Thermo Fisher Scientific MKK7 Polyclonal Antibody
MKK7 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, Flow Cytometry에 적용 가능. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공. 인간, 마우스, 랫트 등 다양한 종에 반응.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.25 µg/mL |
| Immunohistochemistry (Paraffin) (IHC-P) | 1–2 µg/mL |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg / 1×10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human MEK7 (2–40aa AASSLEQKLSRLEAKLKQENREARRRIDLNLDISPQRPR) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746743 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
The protein encoded by this gene is a dual specificity protein kinase belonging to the MAP kinase family. It specifically activates MAPK8/JNK1 and MAPK9/JNK2, and is itself activated by MAP kinase kinases such as MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase mediates cellular responses to proinflammatory cytokines and environmental stresses. Multiple alternatively spliced transcript variants exist, but only one has been well characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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