Thermo Fisher Scientific HSPBAP1 Polyclonal Antibody

Product Specifications

Product Specific Information

Immunogen sequence:
LQQPAIFCNM VFDWPARHWN AKYLSQVLHG KQIRFRMGMK SMSTVPQFET TCNYVEATLE EFLTWNCDQS SISGPFRDYD HSKFWAYADY KYFVSLFEDK TDLFQDVKWS DFGFPGRNGQ ESTLWIGSLG AHTPCHLDSY GCNLVFQ

Target Information

HSPBAP1 (HSPB (heat shock 27kDa) associated protein 1), also known as PASS1 (protein associated with small stress protein 1), is a 488 amino acid cytoplasmic protein that contains one JMJC (Jumonji C) domain and shares 80% identity with its rat homolog, PASS1.
It is widely expressed, with highest expression in ovary, thymus, and pancreas, and is thought to play a role in mediating cellular stress responses within the cell.
Due to the presence of a JMJC domain, HSPBAP1 may be involved in chromatin remodeling events.
Defects or translocations in the gene encoding HSPBAP1 are associated with renal cell carcinoma 1 (RCC1), suggesting a possible role for HSPBAP1 in carcinogenesis.
Three isoforms of HSPBAP1 exist due to alternative splicing events.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.