Thermo Fisher Scientific HEY1 Polyclonal Antibody
HEY1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 유래 폴리클로날 항체. Western blot에 적합하며, 인간 및 설치류에서 높은 교차 반응성을 보임. Notch 신호전달 경로 연구 및 심혈관 발달 관련 연구에 유용. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1.0 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human HEY1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689577 |
Product Specific Information
This target displays homology in the following species:
- Cow: 79%
- Dog: 79%
- Guinea Pig: 100%
- Horse: 93%
- Human: 100%
- Mouse: 93%
- Rat: 100%
Target Information
Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1) belongs to the HEY family and is a Notch signaling pathway protein.
It contains one basic helix-loop-helix (bHLH) domain and one Orange domain.
HEY1 acts as a downstream effector of Notch signaling, which may be required for cardiovascular development.
It functions as a transcriptional repressor that binds preferentially to the canonical E-box sequence 5'-CACGTG-3', repressing transcription by cardiac transcriptional activators GATA4 and GATA6.
HEY1 is also expressed during nervous system development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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