Thermo Fisher Scientific Calpain 12 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human Calpain 12. Recombinant protein control fragment (Product #RP-104095). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Calpain 12,uniProtId:Q6ZSI9-1,ncbiNodeId:9606,antigenRange:510-596,antigenLength:719,antigenImageFileName:PA5-62775_Calpain_12_Q6ZSI9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62775_Calpain_12_Q6ZSI9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639243

Product Specific Information

Immunogen sequence: GDEADFTLRV FSERRHTAVE IDDVISADLQ SLQGPYLPLE LGLEQLFQEL AGEEEELNAS QLQALLSIAL EPARAHTSTP REIGLRT

Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

Target Information

The calpains including Calpain 1 (CAPN1), calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.