Thermo Fisher Scientific Calpain 12 Polyclonal Antibody
Human Calpain 12을 인식하는 Rabbit Polyclonal Antibody로, ICC/IF에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, PBS 기반 버퍼에 40% 글리세롤이 포함되어 있습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human Calpain 12. Recombinant protein control fragment (Product # RP-104095) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2639243 |
Product Specific Information
Immunogen sequence:
GDEADFTLRV FSERRHTAVE IDDVISADLQ SLQGPYLPLE LGLEQLFQEL AGEEEELNAS QLQALLSIAL EPARAHTSTP REIGLRT
Sequence identity:
- Mouse: 83%
- Rat: 80%
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal and intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits associated with a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76, Autosomal Recessive and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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