Thermo Fisher Scientific Human ZBTB5 Synthetic Peptide
인간 ZBTB5 단백질의 카복시 말단 부위 16개 아미노산 서열로 구성된 합성 펩타이드. PA5-21085 항체의 블로킹 펩타이드로 사용 가능. 세포 주기 조절 연구 및 전사 억제 기전 분석에 활용. 연구용으로만 사용 가능.
- 카탈로그번호
- PEP1199
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 16-amino-acid sequence near the carboxy terminus of human ZBTB5.
PEP-1199 can be used as a blocking peptide with polyclonal antibody PA5-21085.
Target Information
The ZBTB family of proteins consists of diverse zinc finger proteins that also contain a BTB (BR-C, ttk, and bab) domain.
ZBTB5 was identified through sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. It binds DNA and directly represses transcription of the cell cycle arrest gene p21.
ZBTB5 interacts with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, leading to deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter.
ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting it may act as a potential proto-oncogene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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