Thermo Fisher Scientific PR3 Polyclonal Antibody
Rabbit polyclonal antibody against human PRTN3 for research use only. Recognizes serine protease PR3 involved in neutrophil migration and vascular integrity. Supplied as unconjugated liquid, 0.1 mg/mL concentration, stored at -20°C for long term.
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Thermo Fisher Scientific PR3 Polyclonal Antibody
제품 개요
Thermo Fisher Scientific의 PR3 Polyclonal Antibody는 인간 PRTN3 단백질을 인식하는 Rabbit IgG 형 다클론 항체입니다. 연구용으로만 사용되며, 진단용으로는 적합하지 않습니다.
제품 사양
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PRTN3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789384 |
Product Specific Information
Immunogen sequence:
PTQQHFSVAQ VFLNNYDAEN KLNDILLIQL SSPANLSASV ATVQLPQQDQ PVPHGTQCLA MGWGRVGAHD PPAQVLQELN VTVVTFFCRP HNICTFVPRR KAGICFGDSG GPLICDGI
Target Information
Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) (PubMed:3198760, PubMed:2033050, PubMed:28240246).
By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration (PubMed:23202369).
May play a role in neutrophil transendothelial migration, probably when associated with CD177 (PubMed:22266279). [UniProt]
주의사항
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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