Thermo Fisher Scientific NF2 Polyclonal Antibody
NF2 단백질(Merlin)을 검출하는 Thermo Fisher Scientific의 rabbit polyclonal 항체로, WB 및 ICC/IF에 적합합니다. 인간, 생쥐, 랫트에 반응하며 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human NF2 (Accession P35240), corresponding to amino acid residues P492–L542 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2900284 |
Product Specific Information
Antibody detects endogenous levels of total NF2 / Merlin.
Target Information
NF2 encodes the protein Merlin, which is similar to members of the ERM family that link cytoskeletal components to membrane proteins. Merlin interacts with cell-surface proteins, cytoskeletal regulators, and ion transport proteins.
This gene is highly expressed during embryonic development and in adults is found in Schwann cells, meningeal cells, lens, and nerve.
Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities.
Two predominant isoforms and several minor isoforms are produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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