Thermo Fisher Scientific CLEC2A Polyclonal Antibody
Human CLEC2A 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. 합성 펩타이드 면역원으로 제작되었으며, PBS 버퍼에 보관됩니다. T세포 확장 조절 연구 및 CLEC2A 신호전달 관련 연구에 적합합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal region of Human CLEC2A (aa 114-163) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2884774 |
Product Specific Information
- Immunogen sequence: HWIGLSRKQG DSWKWTNGTT FNGWFEIIGN GSFAFLSADG VHSSRGFIDI
- Storage guidance:
- Short term: 2–8°C, up to 1 week
- Long term: -20°C, store in small aliquots to prevent freeze-thaw cycles
- Predicted homology:
- Cow: 86%
- Human: 100%
Target Information
CLEC2A (C-type lectin domain family 2 member A), also known as PILAR (proliferation-induced lymphocyte-associated receptor), is involved in modulating T-cell expansion.
It is a 32 kDa single-pass type II membrane protein containing one C-type lectin domain in its extracellular region, belonging to the CTL/CTLD superfamily.
CLEC2A is mainly expressed in skin and highly expressed in CD8(+), B lymphocytes, and naive CD4(+) T cells. Manipulation of CLEC2A signaling may be important for treatment of autoimmune diseases and cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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