Thermo Fisher Scientific PTRF Polyclonal Antibody
Human PTRF 단백질을 표적으로 하는 Rabbit Polyclonal Antibody로, Western blot 및 Immunoprecipitation에 적합. 항원 친화 크로마토그래피로 정제된 액상형 항체. TBS buffer에 0.1% BSA 및 sodium azide 포함, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 125 and 175 of Human RNA polymerase I and transcript release factor (PTRF) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3′ end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and plays a critical role in caveolae formation and stabilization of caveolins. It translocates from caveolae to the cytoplasm after insulin stimulation and is implicated in lipid metabolism and insulin-regulated gene expression. Mutations in this gene are associated with generalized lipodystrophy and muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: A301-269A_PTRF_Q6NZI2-1_Rabbit_PDP.jpeg)
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