Thermo Fisher Scientific PTRF Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

The recommended shelf life for this product is 1 year from date of receipt.

Target Information

Polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3′ end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and plays a critical role in caveolae formation and stabilization of caveolins. It translocates from caveolae to the cytoplasm after insulin stimulation and is implicated in lipid metabolism and insulin-regulated gene expression. Mutations in this gene are associated with generalized lipodystrophy and muscular dystrophy.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

제품 이미지

(이미지 파일명: A301-269A_PTRF_Q6NZI2-1_Rabbit_PDP.jpeg)