Thermo Fisher Scientific Fibrillin 1 Monoclonal Antibody (CL0226)
인간 Fibrillin 1 단백질을 인식하는 Mouse monoclonal antibody(CL0226). IHC(P)에서 1:50–1:200 희석으로 사용 가능. Protein A 정제, PBS(glycerol 포함) 완충액에 보관. 연구용으로만 사용.
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Applications and Tested Dilution
- Immunohistochemistry (Paraffin) [IHC (P)]: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CL0226 |
| Immunogen | Recombinant protein corresponding to Human Fibrillin 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2848878 |
Product Specific Information
Immunogen sequence:
DVRPGYCYTA LTNGRCSNQL PQSITKMQCC CDAGRCWSPG VTVAPEMCPI RATEDFNKLC SVPMVIPGRP EYPPPPLGPI PPVLPVPPGF PPGPQIPVPR PPVEYLYPSR EPPRVLPVNV TDYCQLVRYL CQNGRCIPTP GSCRCEC
Target Information
Fibrillin 1 is an extracellular acidic protein with a high cysteine content and an extended thread-like shape with a mosaic composition of different types of extracellular modules. Most of the fibrillin molecule consists of 47 epidermal growth factor-like (EGF-like) repeats, 43 of which have a consensus sequence for calcium binding. Other modules, including 8-cysteine motifs (seven), hybrid motifs (two), and unique domains (three), are interspersed throughout the molecule. Fibrillin 1 contains a proline-rich region near the N-terminus that is replaced by a glycine-rich region in Fibrillin 2. The fibrillins are found throughout connective tissue as integral components of extended fibrils.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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