Thermo Fisher Scientific HSPA1L Polyclonal Antibody, MaxPab
HSPA1L 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody입니다. Western blot 및 in situ PLA에 적합하며, 인간 및 마우스 시료에서 반응합니다. Affinity chromatography로 정제된 액상 형태로, PBS(pH 7.4)에 보존제가 없습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
in situ PLA (PLA)
- Tested Dilution: 1:1,200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | HSPA1L (AAH34483.1, 1–641 a.a.) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MATAKGIAIG IDLGTTYSCV GVFQHGKVEI IANDQGNRTT PSYVAFTDTE RLIGDAAKNQ VAMNPQNTVF DAKRLIGRKF NDPVVQADMK LWPFQVINEG GKPKVLVSYK GENKAFYPEE ISSMVLTKLK ETAEAFLGHP VTNAVITVPA YFNDSQRQAT KDAGVIAGLN VLRIINEPTA AAIAYGLDKG GQGERHVLIF DLGGGTFDVS ILTIDDGIFE VKATAGDTHL GGEDFDNRLV SHFVEEFKRK HKKDISQNKR AVRRLRTACE RAKRTLSSST QANLEIDSLY EGIDFYTSIT RARFEELCAD LFRGTLEPVE KALRDAKMDK AKIHDIVLVG GSTRIPKVQR LLQDYFNGRD LNKSINPDEA VAYGAAVQAA ILMGDKSEKV QDLLLLDVAP LSLGLETAGG VMTALMKRNS TIPTKQTQIF TTYSDNQPGV LIQVYEGERA MTKDNNLLGR FDLTGIPPAP RGVPQIEVTF DIDANGILNV TAMDKSTGKV NKITIANDKG RLSKEEIERM VLDAEKYKAE DEVQREKIAA KNALESYAFN MKSVVSDEGL KGKISESDKN KILDKCNELL SWLEVNQLAE KDEFDHKRKE LEQMCNPIIT KLYQGGCTGP ACGTGYVPGR PATGPTIEEV D
Target Information
In response to adverse environmental changes, cells increase the expression of heat shock proteins (HSPs). The small heat shock proteins (15–30 kDa) include diverse forms found in yeast, humans, and higher plants. Elevated stress protein expression has been linked to neoplasia, with Hsp27 showing rapid phosphorylation in response to mitogens, tumor promoters, and calcium ionophores. The 24 kDa estrogen-induced protein correlates with steroid hormone receptor expression and is highly expressed in breast carcinoma and endometrial adenocarcinomas. Regulation of human Hsp27 by estrogens and heat shock parallels the ecdysteroid and heat shock activation of Drosophila Hsp20 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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