Thermo Fisher Scientific HSPA1L Monoclonal Antibody (1B5)
HSPA1L 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody (Clone 1B5). Western blot 및 ELISA에 적합하며, Human과 Rat 시료에 반응. PBS buffer에 보존된 액상 형태로, -20°C에서 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B5 |
| Immunogen | HSPA1L (NP_005518, 561–641 a.a.) partial recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
KGKISESDKN KILDKCNELL SWLEVNQLAE KDEFDHKRKE LEQMCNPIIT KLYQGGCTGP ACGTGYVPGR PATGPTIEEV D
Target Information
In response to environmental stress, cells increase expression of heat shock proteins (HSPs). Among them, small heat shock proteins (15–30 kDa) play key roles in stress response and cellular protection. Elevated expression of stress proteins has been associated with neoplastic transformation, as shown in studies on estrogen-induced proteins in breast cancer cells. Hsp27, a 24 kDa estrogen-induced protein, is highly expressed in breast carcinoma and correlates with steroid hormone receptor presence. Similar regulatory mechanisms are observed in endometrial adenocarcinomas and resemble hormone and heat shock regulation in Drosophila Hsp20 genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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