Thermo Fisher Scientific Interferon alpha-2 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:2,000

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:50–1:200

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total Interferon alpha 2.

Target Information

IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in activation of signaling pathways mainly involved in innate immune responses against viral infection.
In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including mammals, birds, reptiles, and fish.
IFN alpha is produced primarily by plasmacytoid dendritic cells, acts as a potent component of the antiviral innate immune response, and modulates adaptive immunity.
Diseases associated with dysfunction of IFN alpha include Hepatitis C and Hepatitis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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