Thermo Fisher Scientific Interferon alpha-2 Polyclonal Antibody
인간 Interferon alpha-2를 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 실험에 최적화됨. 고순도 Affinity chromatography 정제, 1 mg/mL 농도, PBS/glycerol buffer에 보관. 면역반응 및 바이러스 감염 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human IFNA2 (Accession P01563), corresponding to amino acid residues A2–C52 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2850329 |
Product Specific Information
Antibody detects endogenous levels of total Interferon alpha 2.
Target Information
IFN alpha (Interferon alpha) is a Type I interferon belonging to a family of structurally related, species-specific proteins exclusive to vertebrates. The interaction of IFN-alpha with its receptor components results in activation of signaling pathways mainly involved in innate immune responses against viral infection.
In humans, the gene for IFN alpha is located on chromosome 9. Type I interferons consist of 14 different alpha isoforms and single beta, omega, epsilon, and kappa isoforms. Homologous molecules are found in many species, including mammals, birds, reptiles, and fish.
IFN alpha is produced primarily by plasmacytoid dendritic cells, acts as a potent component of the antiviral innate immune response, and modulates adaptive immunity.
Diseases associated with dysfunction of IFN alpha include Hepatitis C and Hepatitis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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