Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI3F9), TrueMAB
SPAG5 단백질을 표적으로 하는 Mouse Monoclonal Antibody (Clone OTI3F9). Western blot에 최적화되어 있으며, Human 시료에 반응. Affinity chromatography로 정제된 1 mg/mL 액상 항체로, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): 1:2,000 dilution tested
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–297 of human SPAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST, or Astrin, is a 1,193 amino acid protein expressed at high levels in testis and at lower levels in liver, placenta, pancreas, colon, and thymus. It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing an essential role in proper spindle formation. SPAG5 is involved in mitotic spindle regulation, sister chromatid cohesion, and chromosome integrity. The protein forms a homodimer with a long stalk and globular head domain, creating aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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