Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI6G2), TrueMAB
SPAG5 단백질을 인식하는 Mouse monoclonal 항체로 Western blot에 적합합니다. 인간 시료에 반응하며, 고순도 친화 크로마토그래피 정제 제품입니다. 액상 형태로 제공되며, 안정적인 PBS/BSA/glycerol 완충액에 보존됩니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–297 of human SPAG5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein highly expressed in testis and at lower levels in liver, placenta, pancreas, colon, and thymus. It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing an essential role in spindle formation and mitotic regulation. SPAG5 also contributes to sister chromatid cohesion and separation, maintaining chromosome integrity. The protein forms homodimers with a long stalk and globular head domain, creating aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only. Not for use in diagnostic procedures or resale without express authorization.
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