Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
Beclin 1 단백질을 인식하는 Thermo Fisher Scientific의 Sheep Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 원숭이, 랫트에 반응. 자가포식 관련 연구용으로 사용. 냉장 또는 냉동 보관 권장.
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Applications
Western Blot (WB)
- Tested Dilution: 10–50 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 10–50 µg/mL
Miscellaneous PubMed (Misc)
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Beclin-1 conjugated to blue carrier protein |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
- Specificity: Beclin-1.
Target Information
Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms are involved in multiple membrane trafficking pathways:
- PI3KC3-C1: Initiation of autophagosomes
- PI3KC3-C2: Maturation of autophagosomes and endocytosis
Beclin 1 also contributes to antiviral host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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