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Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
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Thermo Fisher Scientific Beclin 1 Polyclonal Antibody

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Beclin 1 단백질을 인식하는 Thermo Fisher Scientific의 Sheep Polyclonal Antibody. Western blot 및 IHC에 적합하며 인간, 마우스, 원숭이, 랫트에 반응. 자가포식 관련 연구용으로 사용. 냉장 또는 냉동 보관 권장.

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pk
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Thermo Fisher Scientific OSB00001G-500UG Beclin 1 Polyclonal Antibody 500 ug pk판매 단위 pk
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Thermo Fisher Scientific · Thermo Fisher Scientific Beclin 1 Polyclonal Antibody

Applications

Western Blot (WB)

  • Tested Dilution: 10–50 µg/mL

Immunohistochemistry (IHC)

  • Tested Dilution: 10–50 µg/mL

Miscellaneous PubMed (Misc)


Product Specifications

항목 내용
Species Reactivity Human, Mouse, Non-human primate, Rat
Published Species Not Applicable
Host / Isotype Sheep / IgG
Class Polyclonal
Type Antibody
Immunogen A synthetic peptide from human Beclin-1 conjugated to blue carrier protein
Conjugate Unconjugated
Form Lyophilized
Concentration Not Determined
Purification Ammonium sulfate precipitation
Storage Buffer PBS
Contains No preservative
Storage Conditions Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability.
Shipping Conditions Ambient (domestic); Wet ice (international)

Product Specific Information

  • Reconstitute in 500 µL of sterile water. Centrifuge to remove any insoluble material.
  • The antigen is homologous in rat and mouse.
  • Specificity: Beclin-1.

Target Information

Beclin 1 plays a central role in autophagy as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different PI3K complex forms are involved in multiple membrane trafficking pathways:

  • PI3KC3-C1: Initiation of autophagosomes
  • PI3KC3-C2: Maturation of autophagosomes and endocytosis

Beclin 1 also contributes to antiviral host defense.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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