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Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
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Beclin 1 단백질을 인식하는 Thermo Fisher Scientific의 sheep 유래 polyclonal antibody. Western blot 및 IHC에 적합하며, autophagy 연구에 활용 가능. Lyophilized 형태로 제공되며, 장기 저장 시 -20°C 보관 권장.
- 판매단위
- pk
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662,400원VAT 포함 728,640원
Thermo Fisher Scientific · Thermo Fisher Scientific Beclin 1 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 10–50 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 10–50 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Sheep / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from human Beclin-1 conjugated to blue carrier protein has been used as the antigen. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_962042 |
Product Specific Information
- Reconstitute with 500 µL of distilled water.
- Centrifuge to remove any insoluble material.
- The antigen is homologous in rat and mouse.
Target Information
Beclin 1 plays a central role in autophagy. It acts as a core subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate. Different PI3K complex forms are believed to play a role in multiple membrane trafficking pathways:
- PI3KC3-C1 is involved in the initiation of autophagosomes.
- PI3KC3-C2 is involved in the maturation of autophagosomes and endocytosis.
Beclin 1 also plays a role in antiviral host defense.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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