Thermo Fisher Scientific Seryl-tRNA synthetase Polyclonal Antibody
Rabbit polyclonal antibody recognizing human Seryl-tRNA synthetase. Validated for Western blot with high specificity. Recommended for use with 293T and A431 cell lysates. Predicted cross-reactivity with mouse, rat, and bovine. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 347–514 of human Seryl-tRNA synthetase (UniProt ID: P49591-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.23 mg/mL |
| Storage Conditions | Store at 4°C (short term). For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545091 |
Product Specific Information
- Recommended positive controls: 293T, A431
- Predicted reactivity: Mouse (89%), Rat (92%), Bovine (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Seryl-tRNA synthetase (SerRS) catalyzes the attachment of serine to tRNA(Ser) in a two-step reaction:
- Serine is first activated by ATP to form Ser-AMP.
- Serine is then transferred to the acceptor end of tRNA(Ser).
It may also aminoacylate tRNA(Sec) with serine to form L-seryl-tRNA(Sec), which can be further converted into selenocysteinyl-tRNA(Sec).
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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