Thermo Fisher Scientific RAE1 Polyclonal Antibody
RAE1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot과 Immunocytochemistry에 적합. 고순도 항원 친화 크로마토그래피로 정제된 액상 제품. 다양한 종에 높은 예측 반응성을 보이며 연구용으로 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 307–368 of RAE1 (Uniprot ID: P78406) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11155246 |
Product Specific Information
- Recommended positive controls: HeLaS3, Molt-4, Raji
- Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Pig (100%), Chicken (100%), Chimpanzee (100%), Bovine (100%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes cause accumulation of poly-containing mRNA in the nucleus, suggesting involvement in RNA export. The human homolog RAE1 contains four WD40 motifs and localizes to distinct foci in the nucleoplasm, nuclear rim, and cytoplasmic meshwork-like structures. It is implicated in nucleocytoplasmic transport and in connecting cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been identified.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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