Thermo Fisher Scientific PNLDC1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human PNLDC1. Recombinant protein control fragment (Product #RP-101348). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PNLDC1,uniProtId:Q8NA58-1,ncbiNodeId:9606,antigenRange:253-326,antigenLength:520,antigenImageFileName:PA5-62535_PNLDC1_Q8NA58-1_Rabbit.svg,antigenImageFileNamePDP:PA5-62535_PNLDC1_Q8NA58-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.12 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2645705

Product Specific Information

Immunogen sequence: VGHNMMMDLL HLHEKFFRPL PESYDQFKQN IHSLFPVLID TKSVTKDIWK EMNFPRVSNL SEVYEVLNSD LNPT

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Target Information

3`-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails (PubMed:27515512). Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development (PubMed:27515512). May act as a regulator of multipotency in embryonic stem cells. [UniProt]

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.