Thermo Fisher Scientific Phospho-CD142 (Ser290) Polyclonal Antibody
인간 Coagulation Factor III의 Ser290 인산화 부위를 인식하는 Rabbit Polyclonal 항체. Western Blot 및 IHC(Paraffin) 적용 가능. 액상 형태로 제공되며, -20°C 보관. 연구용으로 혈액 응고 관련 단백질 분석에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human Coagulation Factor III around the phosphorylation site of Ser290 (E-N-SP-P-L) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555058 |
Target Information
This gene encodes coagulation factor III, a cell surface glycoprotein that enables cells to initiate the blood coagulation cascade. It functions as a high-affinity receptor for coagulation factor VII, forming a complex that catalyzes the initiation of protease cascades via limited proteolysis. Unlike other cofactors that circulate as inactive precursors, this factor is fully functional when expressed on cell surfaces. It consists of three domains: extracellular, transmembrane, and cytoplasmic. No congenital deficiency has been described for this protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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