Thermo Fisher Scientific CSK Recombinant Rabbit Monoclonal Antibody (5H3L21)

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Mouse, Pig.

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The antibody DNA sequences from immunoreactive rabbits are cloned and screened to select optimal candidates.
Advantages include:

• Better specificity and sensitivity
• Lot-to-lot consistency
• Animal origin-free formulation
• Broader immunoreactivity due to the large rabbit immune repertoire

Target Information

CSK is a tyrosine kinase that downregulates SRC oncoprotein activity by phosphorylating its carboxy terminus. The CSK gene may act as an antioncogene, regulating cell growth, differentiation, migration, and immune responses.
CSK phosphorylates tyrosine residues in the C-terminal tails of Src-family kinases such as LCK, SRC, HCK, FYN, LYN, CSK, and YES1. It is expressed ubiquitously (~50 kDa) in cytosol, with a fraction localized to lipid rafts via interaction with PAG (Csk-binding protein).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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