
Thermo Fisher Scientific USH1C Monoclonal Antibody (OTI2E12)
USH1C 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. Human 및 Mouse 시료에 반응하며, 동결건조 형태로 제공됩니다. 재구성 후 약 1 mg/mL 농도로 사용 가능하며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 294–552 of human USH1C (NP_005700) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The USH1C gene encodes a scaffold protein involved in the assembly of Usher protein complexes. The protein contains PDZ domains, a coiled-coil region with a bipartite nuclear localization signal, and a PEST degradation sequence.
Mutations in this gene are associated with Usher syndrome type 1C and non-syndromic sensorineural deafness autosomal recessive type 18.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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