Thermo Fisher Scientific CD104 (Integrin beta 4) Polyclonal Antibody
Thermo Fisher Scientific의 CD104 (Integrin beta 4) 폴리클로날 항체는 인간 반응성 Rabbit IgG 기반 항체로, WB, IHC, ICC, Flow Cytometry 등 다양한 응용에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, -20°C에서 안정적으로 보관됩니다.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1 µg/mL |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL |
| Flow Cytometry (Flow) | 1–3 µg/1×10⁶ cells |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human Integrin beta 4 recombinant protein (Position: N28–A266) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746656 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Integrins are heterodimers comprised of alpha and beta subunits that form noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides create complexes with varied ligand-binding specificities.
Integrins mediate cell-matrix or cell-cell adhesion and transduce signals regulating gene expression and cell growth.
This gene encodes the integrin beta 4 subunit, a receptor for laminins, often associated with the alpha 6 subunit. It plays a pivotal role in invasive carcinoma biology.
Mutations in this gene are linked to epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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